Topical Spray
5%
Product Overview
Valproic Acid Description1-4
Valproic acid is an antiepileptic medication used in the treatment of partial and absence seizures. While it is most commonly prescribed for seizure disorders, data suggest that valproic acid may support hair growth in individuals with androgenetic alopecia. The effects of topical valproic acid on hair growth have been demonstrated in in vitro culture studies, animal models involving mice, and in a randomized controlled trial conducted in men with androgenetic alopecia. In that randomized controlled trial, valproic acid was associated with an increase in hair count in men with androgenetic alopecia.
Mechanism of Action1-4
The mechanism of how valproic acid stimulates hair growth is related to intracellular pathways and targets. Coordination of signaling between cells is important for formation and maintenance of the hair follicle. β-Catenin is critical for the development and growth of hair follicles through Wnt signaling. Without Wnt signals, β-catenin is phosphorylated by glycogen synthase kinase (GSK)-3 and then degraded. Inhibiting GSK-3 may enhance hair growth. Valproic acid may inhibit GSK-3 to facilitate hair growth.
Common 4
Contraindications1-4
Precautions1-4
Store at 2°C–8°C (36°F–46°F). Protect from light, heat, and moisture.
WPPL operates as a 503A compounding pharmacy and prepares individualized prescription medications pursuant to provider direction. Compounded preparations are not reviewed, tested, or approved by the FDA.
This listing also includes commercially manufactured products for convenience; these items are not compounded by our pharmacy and are sold as provided by their manufacturers. Actual products in stock at time of dispensing may vary due to supply chain variability. Any statements regarding non-compounded products are manufacturer-supplied, have not been evaluated by the FDA, and are not intended to diagnose, treat, cure, or prevent any disease. WPPL does not verify or endorse any therapeutic claims made by manufacturers. Please refer to original labeling for complete product information.
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Providers: Let’s Partner for Better Patient Care
If you are a physician, clinic, or practice seeking a dependable Compounding Pharmacy partner, WP Pharma Labs is here to help. With dedicated account setup, streamlined ordering and responsive service, we support your therapeutic goals with specialized compounds designed for your patients.
To check product availability, check on the status of an existing order, request refills:
orders@wppharmalabs.com
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