Biotin / Finasteride

Capsule

5 mg / 1 mg

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Product Overview

Biotin Description 1,2,3

Biotin (vitamin B7) is a water-soluble vitamin that functions as a cofactor in numerous cellular reactions, including the metabolism of fats, proteins, and carbohydrates. Biotin also plays a role in gene expression and influences DNA-related processes, including fetal development and the regulation of synthesis and breakdown of fats, proteins, and sugars, in addition to its direct catalytic activity.

Biotin deficiency is uncommon in individuals consuming a balanced diet; however, when deficiency occurs, it may present with symptoms such as dry skin, seborrheic dermatitis, fungal infections, skin rashes, fine or brittle hair, and hair thinning or complete alopecia. Although true biotin deficiency is rare, available evidence indicates no associated harm with biotin supplementation.

Finasteride Description 4,5,6

Finasteride is a 5-alpha reductase inhibitor that has demonstrated benefit in patients with symptomatic benign prostatic hyperplasia, a condition commonly affecting men over the age of 50. Finasteride has also been shown to be beneficial in the treatment of androgenetic alopecia (male pattern hair loss).

References

  1. Biotin – Fact sheet for health professionals; NIH; 2025; https://ods.od.nih.gov/factsheets/Biotin-HealthProfessional/#en3
  2. Biotin – Fact sheet for consumers; NIH; 2025; https://ods.od.nih.gov/factsheets/Biotin-Consumer/
  3. Biotin – Drugbank ; 2025; https://go.drugbank.com/drugs/DB00121
  4. Finasteride (Proscar) package insert. Issued October 2010. Accessed June 3, 2025 accessdata.fda.gov/drugsatfda_docs/label/2010/020180s037lbl.pdf
  5. Finasteride (Propecia) package insert. Revised April 2012. Accessed June 3, 2025 accessdata.fda.gov/drugsatfda_docs/label/2012/020788s020s021s023lbl.pdf
  6. Clinical Pharmacology finasteride clinical monograph 2025 https://www.clinicalkey.com/pharmacology/

Biotin Mechanism of Action1,2,3

Biotin serves as a coenzyme that binds directly to four enzymes that are responsible for the synthesis of macronutrients (fat, protein, sugar) and other molecules.  Biotin also regulates our genes by effecting the way in which our DNA is presented within cells (histone modification), this has been shown to influence immune function and fetal development.

Finasteride Mechanism of Action 4,5,6

Finasteride is an analog of testosterone that acts as a competitive, specific inhibitor of type II 5-alpha-reductase, an intracellular enzyme that converts testosterone to the potent androgen 5-alpha-dihydrotestosterone. The type II 5-alpha-reductase isozyme is primarily found in prostate, seminal vesicles, epididymides, and hair follicles, as well as liver. Dihydrotestosterone has been shown to increase prostate growth and can lead to hair thinning. Finasteride has been shown to shrink the prostate to improve urinary flow and in the scalp lowers dihydrotestosterone to slow hair loss and promote regrowth.

Biotin Adverse Reactions1,2,3

  • There are no documented adverse reactions to biotin supplementation.

Finasteride Adverse Reactions 4,5,6

  • Decreased libido
  • Erectile dysfunction
  • Ejaculatory disorders (e.g., reduced volume)
  • Breast tenderness or enlargement
  • Gynecomastia

Biotin Contraindications & Precautions1,2,3

Contraindications

  • There are no contraindications to biotin supplementation

Precautions

  • Biotin has been shown to interfere with lab results when taken as a supplement in higher doses, particularly hormone panels and especially thyroid hormone; always tell your healthcare provider if you are taking biotin, or any other supplements or medications.

 

Finasteride Contraindications & Precautions 4,5,6

Contraindications

  • Contraindicated in women who are or may become pregnant due to risk of teratogenicity (can cause abnormalities in the external genitalia of male fetuses)
  • Hypersensitivity to finasteride or any component of the tablet

Precautions

  • Finasteride lowers serum PSA levels by ~50% after 6 months, which can mask early detection of prostate cancer.
  • Use cautiously in patients with hepatic dysfunction. The drug is metabolized extensively in the liver.
  • Store at controlled room temperature (20°C to 25°C / 68°F to 77°F)
  • Protect from moisture and light
  • Keep in a tightly closed container
  1. Biotin – Fact sheet for health professionals; NIH; 2025; https://ods.od.nih.gov/factsheets/Biotin-HealthProfessional/#en3
  2. Biotin – Fact sheet for consumers; NIH; 2025; https://ods.od.nih.gov/factsheets/Biotin-Consumer/
  3. Biotin – Drugbank ; 2025; https://go.drugbank.com/drugs/DB00121
  4. Finasteride (Proscar) package insert. Issued October 2010. Accessed June 3, 2025 accessdata.fda.gov/drugsatfda_docs/label/2010/020180s037lbl.pdf
  5. Finasteride (Propecia) package insert. Revised April 2012. Accessed June 3, 2025 accessdata.fda.gov/drugsatfda_docs/label/2012/020788s020s021s023lbl.pdf
  6. Clinical Pharmacology finasteride clinical monograph 2025 https://www.clinicalkey.com/pharmacology/
This information is for educational purposes only.
This compounded product has not been reviewed, approved, or evaluated by the Food and Drug Administration for safety and effectiveness. This product is not intended to diagnose, treat, cure, or prevent any disease. No claims are made regarding treatment, cure, or prevention of any disease or condition.
This information is a summary. It may not cover all possible drug information about this product. For complete product information, refer to the manufacturer’s prescribing information and labeling. Call your doctor for medical advice and/or about side effects. You may report side effects to the FDA at 1-800-FDA-1088. A WP Pharma Labs pharmacist will be happy to answer any questions. For consultation, please call 1-800-441-0048.

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