Phentermine / 7-Keto DHEA / Calcium Pyruvate SR K100

Capsule

15 mg / 10 mg / 100 mg
30 mg / 10 mg / 100 mg
37.5 mg / 10 mg / 100 mg

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Disclaimer: Images are for reference only; actual products may vary.

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Product Overview

Phentermine1-4

Phentermine is a sympathomimetic stimulant of the central nervous system used as an anorectic agent. It is classified as a Schedule IV controlled substance. Phentermine is structurally and pharmacologically similar to amphetamines and is also an analog of methamphetamine. It may be prescribed as a single agent or combined at lower doses with other medications to enhance its effects. Approved in 1959, phentermine is indicated for the following use:

  • Obesity: Short-term management in conjunction with reduced caloric intake and lifestyle modifications for patients with a body mass index (BMI) of 30 kg/m² or greater, or a BMI of 27 kg/m² or greater in the presence of comorbid conditions such as hypertension, diabetes, or dyslipidemia.

7-Keto DHEA5-8

7-Keto-DHEA is a naturally occurring metabolite of dehydroepiandrosterone (DHEA). Unlike DHEA, it does not convert into sex hormones such as testosterone or estradiol. Available evidence suggests potential activity in areas including weight management, metabolic support, immune function, and cognitive performance.

Calcium Pyruvate9-12

Calcium pyruvate is a compound formed during carbohydrate metabolism when glucose is converted into energy. It is the calcium salt of pyruvic acid. Calcium pyruvate has been studied for its anti-inflammatory properties, cardioprotective effects, and potential role in supporting weight loss.

References

  1. Phentermine Package insert. Revised March 2024. Accessed June 20, 2025. https://www.adipex.com/globalassets/adipex/adipex_pi.pdf 
  2. Clinical Pharmacology phentermine clinical monograph 2025 https://www.clinicalkey.com/pharmacology/
  3. Elmaleh-Sachs A, Schwartz JL, Bramante CT, Nicklas JM, Gudzune KA, Jay M. Obesity Management in Adults: A Review. JAMA. 2023 Nov 28;330(20):2000-2015.
  4. Phentermine https://www.ncbi.nlm.nih.gov/books/NBK547916/#Phentermine.OVERVIEW Accessed June 20, 2025.
  5. 7-Keto DHEA – Patient Handout; NatMed Pro; 2025; https://naturalmedicines-therapeuticresearch-com.lp.hscl.ufl.edu/databases/food,-herbs-supplements/patienthandout.aspx?productid=835&lang=en
  6. 7-Keto DHEA – Professional Monograph; NatMed Pro; 2025; https://naturalmedicines-therapeuticresearch-com.lp.hscl.ufl.edu/databases/food,-herbs-supplements/professional.aspx?productid=835
  7. Douglas S. Kaiman, Carlon M. Colker, Melissa A. Swain, Georgeann C. Torina, Qiuhu Shi. A randomized, double-blind, placebo-controlled study of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy overweight adults. Current Therapeutic Research. Volume 61, Issue 7, 2000, 435-442.
  8. Jeyaprakash N, Maeder S, Janka H, Stute P. A systematic review of the impact of 7-keto-DHEA on body weight. Arch Gynecol Obstet. 2023 Sep;308(3):777-785.
  9. Nat Med Pyruvate accessed June 23, 2025.
  10. Olek RA, Kujach S, Radak Z. Current knowledge about pyruvate supplementation: A brief review. Sports Med Health Sci. 2024 Feb 28;6(4):295-301.
  11. Onakpoya I, Hunt K, Wider B, Ernst E. Pyruvate supplementation for weight loss: a systematic review and meta-analysis of randomized clinical trials. Crit Rev Food Sci Nutr. 2014;54(1):17-23.
  12. Pyruvic Acid. Drug Bank Accessed June 29, 2025.

Phentermine1,2

Phentermine predominantly acts in the central nervous system (CNS), within the hypothalamus and limbic systems, where it works on appetite regulation. It stimulates the release of norepinephrine and dopamine from the nerve, and its reuptake is inhibited. The increased norepinephrine may decrease hunger through a reduction in hungry messaging.

7-Keto DHEA5,6

7-Keto-DHEA is believed to enhance thermogenesis (heat production) and basal metabolic rate by modulating the activity of 3 key metabolic enzymes, including: Glycerol-3-phosphate dehydrogenase, cytosolic malic enzyme, citrate lyase. These enzymes influence fatty acid oxidation and mitochondrial efficiency, contributing to increased energy expenditure by cells.

Calcium Pyruvate10,12

Calcium pyruvate is used as a source of energy to produce ATP aerobically. It is metabolized in the Krebs cycle and converted to acetyl coenzyme A. It can be a source of energy anaerobically when it is converted to lactate.

Phentermine1,2

  • Gastrointestinal-dry mouth, diarrhea, constipation
  • Central nervous system-insomnia, dizziness, restlessness, nervousness, tremor, headache
  • Cardiovascular-tachycardia, increased blood pressure

7-Keto DHEA5,6

  • Headache
  • Nausea or gastrointestinal upset
  • Mild dizziness
  • Irritability
  • Sleep disturbances (less common)

Because it does not convert into sex hormones, androgenic side effects (e.g., acne, hair loss, hirsutism) are rare or absent.

Calcium pyruvate9

  • Orally: Bloating, diarrhea.

Contraindications

Phentermine1,2

  • A known hypersensitivity to phentermine, 7-Keto DHEA, Calcium pyruvate or any of its ingredients
  • Contraindicated in pregnancy
  • Cardiovascular disease (coronary artery disease, arrhythmias, stroke, congestive heart failure, uncontrolled hypertension)
  • Hyperthyroidism
  • Glaucoma
  • History of drug abuse
  • Agitated states or severe anxiety disorders
  • Who have used monoamine oxidase inhibitors (MAOIs) within the past 14 days

 

7-Keto DHEA5,6

  • Hypersensitivity to 7-keto-DHEA or any excipients in the product
  • Pregnancy or breastfeeding (insufficient safety data)

 

Precautions

Phentermine1,2

  • Use with caution in patients with diabetes
  • Use cautiously in people operating machinery or driving a car

 

7-Keto DHEA5,6

  • Use caution in individuals with autoimmune diseases due to theoretical immune-enhancing effects.
  • May interfere with thyroid function tests (e.g., T3/T4 levels); however, clinical significance is unclear.
  • People with hormone-sensitive conditions may still want to consult a healthcare provider, even though 7-keto-DHEA lacks direct hormonal activity.
  • Store at controlled room temperature (20°C to 25°C / 68°F to 77°F)
  • Protect from moisture and light
  • Keep in a tightly closed container
  1. Phentermine Package insert. Revised March 2024. Accessed June 20, 2025. https://www.adipex.com/globalassets/adipex/adipex_pi.pdf 
  2. Clinical Pharmacology phentermine clinical monograph 2025 https://www.clinicalkey.com/pharmacology/
  3. Elmaleh-Sachs A, Schwartz JL, Bramante CT, Nicklas JM, Gudzune KA, Jay M. Obesity Management in Adults: A Review. JAMA. 2023 Nov 28;330(20):2000-2015.
  4. Phentermine https://www.ncbi.nlm.nih.gov/books/NBK547916/#Phentermine.OVERVIEW Accessed June 20, 2025.
  5. 7-Keto DHEA – Patient Handout; NatMed Pro; 2025; https://naturalmedicines-therapeuticresearch-com.lp.hscl.ufl.edu/databases/food,-herbs-supplements/patienthandout.aspx?productid=835&lang=en
  6. 7-Keto DHEA – Professional Monograph; NatMed Pro; 2025; https://naturalmedicines-therapeuticresearch-com.lp.hscl.ufl.edu/databases/food,-herbs-supplements/professional.aspx?productid=835
  7. Douglas S. Kaiman, Carlon M. Colker, Melissa A. Swain, Georgeann C. Torina, Qiuhu Shi. A randomized, double-blind, placebo-controlled study of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy overweight adults. Current Therapeutic Research. Volume 61, Issue 7, 2000, 435-442.
  8. Jeyaprakash N, Maeder S, Janka H, Stute P. A systematic review of the impact of 7-keto-DHEA on body weight. Arch Gynecol Obstet. 2023 Sep;308(3):777-785.
  9. Nat Med Pyruvate accessed June 23, 2025.
  10. Olek RA, Kujach S, Radak Z. Current knowledge about pyruvate supplementation: A brief review. Sports Med Health Sci. 2024 Feb 28;6(4):295-301.
  11. Onakpoya I, Hunt K, Wider B, Ernst E. Pyruvate supplementation for weight loss: a systematic review and meta-analysis of randomized clinical trials. Crit Rev Food Sci Nutr. 2014;54(1):17-23.
  12. Pyruvic Acid. Drug Bank Accessed June 29, 2025.
This information is for educational purposes only.
This compounded product has not been reviewed, approved, or evaluated by the Food and Drug Administration for safety and effectiveness. This product is not intended to diagnose, treat, cure, or prevent any disease. No claims are made regarding treatment, cure, or prevention of any disease or condition.
This information is a summary. It may not cover all possible drug information about this product. For complete product information, refer to the manufacturer’s prescribing information and labeling. Call your doctor for medical advice and/or about side effects. You may report side effects to the FDA at 1-800-FDA-1088. A WP Pharma Labs pharmacist will be happy to answer any questions. For consultation, please call 1-800-441-0048.

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