Anastrozole

(Commercial Product) Tablets

1 mg

Ready to prescribe?
Disclaimer: Images are for reference only; actual products may vary.

Product Overview Coming Soon

Product Overview

Anastrozole Description1

Anastrozole tis a buccal tablet designed to deliver the aromatase inhibitor anastrozole. This compounded formulation allows absorption through the oral mucosa, providing improved bioavailability and convenience compared with traditional oral tablets, particularly for patients who have difficulty swallowing or who prefer a faster onset of action. Anastrozole is used in postmenopausal women with hormone receptor-positive breast cancer.

References

  1. Clinical Pharmacology anastrozole clinical monograph 2025 https://www.clinicalkey.com/pharmacology/

Mechanism of Action1-2

Anastrozole is a selective non-steroidal aromatase inhibitor. In postmenopausal women, estrogens are mainly derived from the action of the aromatase enzyme, which converts adrenal androgens (primarily androstenedione and testosterone) to estrone and estradiol. Suppression of estrogen biosynthesis in peripheral tissues and in cancer cells can be achieved by specifically inhibiting the aromatase enzyme. Therapeutically, this inhibition results in decreased systemic estrogen levels and increased systemic testosterone levels, which is therapeutic in estrogen-dependent breast cancers and in disease states where increased testosterone is important.

Common1

  • Hot flashes
  • Gastrointestinal (nausea, vomiting, abdominal pain)
  • Headache
  • Weight gain
  • Osteopenia
  • Insomnia

Contraindications1-3

  • Known hypersensitivity to anastrozole or any component of the formulation.

Precautions1-3

  • Use with caution in patients with pre-existing hypercholesterolemia.
  • Use with caution in patients with pre-existing osteoporosis; consider bone mineral density (BMD) monitoring in patients treated with anastrozole.
  • Not recommended in patients who are pregnant.
  • Use with caution in patients with pre-existing ischemic cardiac disease.
  • Store at controlled room temperature (20°C to 25°C / 68°F to 77°F)
  • Protect from moisture and light
  • Keep in a tightly closed container
  1. Clinical Pharmacology anastrozole clinical monograph 2025 https://www.clinicalkey.com/pharmacology/
  2. de Ronde W, de Jong FH. Aromatase inhibitors in men: effects and therapeutic options. Reprod Biol Endocrinol. 2011 Jun 21;9:93.
  3. Anastrozole (Ascend Laboratories, LLC): FDA Package Insert. https://medlibrary.org/lib/rx/meds/anstrozole-15/. Anastrozole package insert. Revised 03/11 Accessed May 20, 2025.
This information is for educational purposes only.
WP Pharma Labs distributes certain FDA-approved commercial products that are manufactured by third-party pharmaceutical companies. These products are not compounded or manufactured by WP Pharma Labs. Product availability at the time of dispensing may vary due to supply chain conditions.
This information is a summary. It may not cover all possible drug information about this product. For complete product information, refer to the manufacturer’s prescribing information and labeling. Call your doctor for medical advice and/or about side effects. You may report side effects to the FDA at 1-800-FDA-1088. A WP Pharma Labs pharmacist will be happy to answer any questions. For consultation, please call 1-800-441-0048.

EXPLORE MORE

Related Medications

Licensed to ship across the U.S.

Your orders arrive promptly and privately, delivered directly to your door.

Providers: Let’s Partner for Better Patient Care

If you are a physician, clinic, or practice seeking a dependable Compounding Pharmacy partner, WP Pharma Labs is here to help. With dedicated account setup, streamlined ordering and responsive service, we support your therapeutic goals with specialized compounds designed for your patients.

To check product availability, check on the status of an existing order, request refills:
orders@wppharmalabs.com

New providers setup / update an existing account:
newaccounts@wppharmalabs.com