(Ship Cold) Nasal Spray
0.25% (0.25 mg/Spray) | 0.5% (0.5 mg/Spray)
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Product Overview
Ethylenediaminetetraacetic Acid Description1,2
EDTA has multiple medicinal uses. It functions as a chelating agent for high calcium levels and exposure to heavy metals, including lead. It also acts as an anticoagulant in laboratory hematology tests. Furthermore, EDTA can be applied to help reduce microbial growth in central venous lines as a lock solution and to interfere with biofilm formation by certain bacterial pathogens, including those linked to chronic rhinosinusitis. When used as a nasal spray, EDTA has been examined for its effects on biofilms produced by bacteria such as S. aureus (including methicillin-resistant strains), P. aeruginosa, E. coli, K. pneumoniae, Serratia marcescens, as well as fungi like Candida albicans and Candida glabrata, and may support the activity of antimicrobial agents.
References
Mechanism of Action1,2
EDTA works on sinus infections by weakening the extracellular matrix of the biofilm by sequestering the cations (calcium, magnesium, and zinc) required to maintain the structure of the biofilm. Once the biofilm is destabilized the immune system and antimicrobials can better work to treat the infection.
Common1,2
Contraindications1,2
Precautions1,2
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