Sublingual
0.5 mg | 1 mg | 2.5 mg | 4.5 mg
Product Overview
Semaglutide, SL RDT Description1-6
Semaglutide, SL RDT is a synthetic glucagon-like peptide-1 receptor agonist (GLP-1 RA) and functions as an incretin mimetic. Incretins are hormones released from the gastrointestinal tract into systemic circulation that assist with glycemic regulation and have also been utilized in weight management. When administered orally, semaglutide has been used for the following indication:
• Treatment of type 2 diabetes mellitus as an adjunct to diet and exercise
Available evidence indicates that oral semaglutide may produce clinically meaningful outcomes for individuals seeking weight reduction. In a 68-week study, oral semaglutide was associated with a 15% decrease in body weight.
Mechanism of Action1-6
Semaglutide is an incretin mimetic that works on the glucagon-like peptide-1 (GLP-1) receptor by binding and activating the GLP-1 receptor. It has 94% sequence homology to human GLP-1. GLP-1 medications regulate glucose metabolism after oral consumption of carbohydrates and fats. The drug increases insulin secretion by glucose-dependent insulin synthesis and in vivo secretion of insulin from pancreatic beta cells in the presence of elevated glucose levels. It also suppresses glucagon secretion, slows gastric emptying, reduces food intake, and promotes beta-cell proliferation.
Common 3,4
Gastrointestinal: Nausea, vomiting, diarrhea, constipation, dyspepsia, headache, dizziness.
Contraindications & Precautions3,4
Contraindications:
Precautions:
WPPL operates as a 503A compounding pharmacy and prepares individualized prescription medications pursuant to provider direction. Compounded preparations are not reviewed, tested, or approved by the FDA.
This listing also includes commercially manufactured products for convenience; these items are not compounded by our pharmacy and are sold as provided by their manufacturers. Any statements regarding non-compounded products are manufacturer-supplied, have not been evaluated by the FDA, and are not intended to diagnose, treat, cure, or prevent any disease. WPPL does not verify or endorse any therapeutic claims made by manufacturers. Please refer to original labeling for complete product information.
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Providers: Let’s Partner for Better Patient Care
If you are a physician, clinic, or practice seeking a dependable Compounding Pharmacy partner, WP Pharma Labs is here to help. With dedicated account setup, streamlined ordering and responsive service, we support your therapeutic goals with specialized compounds designed for your patients.
To check product availability, check on the status of an existing order, request refills:
orders@wppharmalabs.com
New providers setup / update an existing account:
newaccounts@wppharmalabs.com
