Ultra-Test (Cypionate 80% / Propionate 20%)

Injection

200 mg/mL

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Product Overview

Ultra-Test Description1-6

Testosterone Cypionate 80% / Propionate 20% Injection is a compounded injectable testosterone ester formulation composed of 80% testosterone cypionate and 20% testosterone propionate. Both esters have been used in testosterone replacement therapy (TRT) for the treatment of male hypogonadism. The inclusion of two esters with differing pharmacokinetic characteristics is intended to provide a stable and sustained release of testosterone, which may help limit injection frequency and reduce variability in hormone levels. Testosterone propionate has an approximate half-life of 4.5 days, while testosterone cypionate has a longer half-life of about 8 days. In comparison, non-esterified testosterone has a half-life as short as 10 minutes, indicating that esterification extends the duration of action.

Mechanism of Action1-6

Testosterone cypionate and testosterone propionate are both esterified forms of testosterone. The esterification occurs on the 17b carbon of the testosterone structure. The esters extend the duration of action and are useful for less frequent, intramuscular, or subcutaneous injections.  Once administered, the esters are cleaved, releasing free testosterone into the bloodstream. Testosterone then binds to androgen receptors in various tissues, exerting anabolic and androgenic effects. Testosterone has a role in influencing the development and maintenance of male secondary sexual characteristics, stimulation of muscle and bone growth, and regulation of libido and mood.

Common1

  • Acne
  • Hypertension
  • Injection site pain or inflammation
  • Mood swings or irritability
  • Increased or decreased libido
  • Gynecomastia

Contraindications1  

  • Known hypersensitivity or intolerance to testosterone or either ester component
  • Males with carcinoma of the breast or known or suspected carcinoma of the prostate
  • Pregnant or breastfeeding women
  • Patients with serious cardiac, hepatic, or renal disease

Precautions1  

  • Monitor hematocrit and hemoglobin levels.
  • Regularly assess liver function tests.
  • Evaluate lipid profiles periodically.
  • Monitor for signs of sleep apnea.
  • Use cautiously in patients with a history of cardiovascular disease.

Store at 20°C to 25°C (68°F to 77°F) in a dry place, away from heat and light. DO NOT REFRIGERATE. Do not freeze. Keep out of reach of children.

  1. Clinical Pharmacology Testosterone clinical monograph accessed September 1 2025 ; https://www.clinicalkey.com/pharmacology/monograph/595?n=Testosterone
  2. Pubchem testosterone propionate. https://pubchem.ncbi.nlm.nih.gov/compound/Testosterone-Propionate Accessed September 1, 2025
  3. Pubchem testosterone cypionate. https://pubchem.ncbi.nlm.nih.gov/compound/Testosterone-Cypionate#section=Metabolism-Metabolites. Accessed July 6, 2025
  4. Testosterone Propionate – Steroids Profile – Steroidal.com. https://www.steroidal.com/steroid-profiles/testosterone-propionate/ June 5, 2019 Accessed September 1, 2025
  5. Mayo Clinic. Testosterone cypionate (intramuscular route). https://www.mayoclinic.org/drugs-supplements/testosterone-cypionate-intramuscular-route/description/drg-20563731
  6. Depo Testosterone(Testosterone Cypionate) [package insert] Pfizer Inc NY, NY 10017, revised July 2018, accessed May 2025 through: https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/085635s040lbl.pdf

WPPL operates as a 503A compounding pharmacy and prepares individualized prescription medications pursuant to provider direction. Compounded preparations are not reviewed, tested, or approved by the FDA.

This listing also includes commercially manufactured products for convenience; these items are not compounded by our pharmacy and are sold as provided by their manufacturers. Actual products in stock at time of dispensing may vary due to supply chain variability. Any statements regarding non-compounded products are manufacturer-supplied, have not been evaluated by the FDA, and are not intended to diagnose, treat, cure, or prevent any disease. WPPL does not verify or endorse any therapeutic claims made by manufacturers. Please refer to original labeling for complete product information.

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