Tablets
2.5 mg
Product Overview Coming Soon
Product Overview
Letrozole Tablets Description1,2
Letrozole is a nonsteroidal aromatase inhibitor that works by suppressing estrogen production through inhibition of the aromatase enzyme. It is primarily used in postmenopausal women for the treatment of hormone receptor–positive breast cancer, including both early-stage disease and advanced or metastatic breast cancer.
References
Mechanism of Action1,2
Letrozole binds to heme group of the cytochrome P450 subunit of the aromatase (enzyme) resulting in a reduction of estrogen (estrone, estradiol and estrone sulfate) biosynthesis in all tissues. The drug decreases estrogen levels by preventing the conversion of androgens to estrogen.
Common1
Contraindications1,2
Precautions1,2
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