(Commercial Product) Tablet
1.5 mg | 4 mg | 9 mg | 25 mg
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Product Overview
Semaglutide Tablet Description1-3
Semaglutide is a synthetic glucagon-like peptide-1 receptor agonist (GLP-1 RA) that functions as an incretin mimetic. Incretins are hormones released from the gastrointestinal tract into the systemic circulation that help support glycemic regulation. This medication is used for the following indications:
For the management of obesity and for long-term weight management when used alongside a reduced-calorie diet and increased physical activity. It is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in: adults who are obese or overweight.
References
Mechanism of Action 1-3
Semaglutide is an incretin mimetic that works on the glucagon-like peptide-1 (GLP-1) receptor by binding and activating the GLP-1 receptor. It has 94% sequence homology to human GLP-1. GLP-1 medications regulate glucose metabolism after oral consumption of carbohydrates and fats. The drug increases insulin secretion by glucose-dependent insulin synthesis and in vivo secretion of insulin from pancreatic beta cells in the presence of elevated glucose levels. It also suppresses glucagon secretion, slows gastric emptying, reduces food intake, and promotes beta-cell proliferation.
Adverse Reactions1-3
Common
Contraindications & Precautions 1-3
Contraindications:
Precautions:
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