(Commercial Product) Tablets
5 mcg | 25 mcg | 50 mcg
Product Overview
Liothyronine Sodium Description1,2
Liothyronine is synthetically produced to act in a manner similar to the endogenous thyroid hormone triiodothyronine. It is available as an oral tablet and is intended for use as replacement or adjunctive therapy in the management of hypothyroidism. The human body produces two primary thyroid hormones: thyroxine (T4) and triiodothyronine (T3), with T3 being the more biologically active form. T3 has a faster onset of action than T4 and may be used in individuals who have limited conversion of T4 to T3.
Liothyronine is indicated for the treatment of:
Hypothyroidism: As replacement therapy in primary (thyroidal), secondary (pituitary), or tertiary (hypothalamic) congenital or acquired hypothyroidism.
Pituitary Thyrotropin (Thyroid-Stimulating Hormone, TSH) Suppression: As an adjunct to surgery and radioiodine therapy in the management of well-differentiated thyroid cancer.
Thyroid Suppression Test: As a diagnostic agent in suppression testing to differentiate suspected mild hyperthyroidism or thyroid gland autonomy.
Mechanism of Action1
Triiodothyronine exerts its physiologic actions through control of DNA transcription and protein synthesis. It does this by entering into the cell nucleus and binding to thyroid receptor proteins attached to DNA. This hormone nuclear receptor complex activates gene transcription and synthesis of messenger RNA and cytoplasmic proteins. The physiological actions of thyroid hormones are produced predominantly by T3.
Common (mimic symptoms of hyperthyroidism)1,2
Temporary hair loss, especially in pediatric patients early in therapy.
Contraindications1
Precautions1
WPPL operates as a 503A compounding pharmacy and prepares individualized prescription medications pursuant to provider direction. Compounded preparations are not reviewed, tested, or approved by the FDA.
This listing also includes commercially manufactured products for convenience; these items are not compounded by our pharmacy and are sold as provided by their manufacturers. Actual products in stock at time of dispensing may vary due to supply chain variability. Any statements regarding non-compounded products are manufacturer-supplied, have not been evaluated by the FDA, and are not intended to diagnose, treat, cure, or prevent any disease. WPPL does not verify or endorse any therapeutic claims made by manufacturers. Please refer to original labeling for complete product information.
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