(Commercial Product) Tablets
4 mg | 8 mg
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Product Overview
Ondansetron Description1,2
Ondansetron is a 5-HT₃ receptor antagonist that is used clinically as an antiemetic. It is utilized to prevent and manage nausea and vomiting, particularly in patients undergoing chemotherapy, receiving radiation therapy, or following surgery or other medical procedures.
References
Mechanism of Action1,2
Serotonin (5-HT₃) receptors are found in the gastrointestinal tract and centrally in the chemoreceptor trigger zone (CTZ) in the brain. Ondansetron prevents serotonin from binding to serotonin receptors in the gastrointestinal tract and the chemoreceptor trigger zone. By preventing serotonin from binding to these receptors, it inhibits vomiting reflexes, specifically when chemotherapy, radiation, and anesthesia is administered.
Common1,2
Contraindications1,2
Precautions1,2
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