Bi-Test (Enanthate 75% / Cypionate 25%)

Injection

200 mg/mL

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Disclaimer: Images are for reference only; actual products may vary.

Product Overview

Bi-Test Description1,2

Bi-Test is a compounded injectable testosterone formulation containing 75% testosterone enanthate and 25% testosterone cypionate. Both components are long-acting testosterone esters that have been used in testosterone replacement therapy (TRT) for the management of male hypogonadism. This blend is designed to utilize the pharmacokinetic characteristics of each ester to support a more consistent and sustained release of testosterone, which may help reduce injection frequency and limit fluctuations in hormone levels.

Mechanism of Action1,2,3,4

Testosterone enanthate and testosterone cypionate are both esterified forms of testosterone, designed for intramuscular injection. Once administered, the esters are cleaved, releasing free testosterone into the bloodstream. Testosterone then binds to androgen receptors in various tissues, exerting anabolic and androgenic effects. These effects include the development and maintenance of male secondary sexual characteristics, stimulation of muscle and bone growth, and regulation of libido and mood.

Adverse Reactions1

  • Acne
  • Hypertension
  • Injection site pain or inflammation
  • Mood swings or irritability
  • Increased or decreased libido
  • Gynecomastia

Contraindications1

  • Known hypersensitivity to testosterone or either ester (cypionate or enanthate).
  • Known hypersensitivity to grapeseed oil.
  • Males with carcinoma of the breast or known or suspected carcinoma of the prostate.
  • Pregnant or breastfeeding women.
  • Patients with serious cardiac, hepatic, or renal disease.

Precautions1

  • Monitor hematocrit and hemoglobin levels.
  • Regularly assess liver function tests.
  • Evaluate lipid profiles periodically.
  • Monitor for signs of sleep apnea.
  • Use cautiously in patients with a history of cardiovascular disease.

Store Bi-Test at 20°C to 25°C (68°F to 77°F) in a dry place, away from heat and light. Do not freeze. Keep out of reach of children.

  1. Clinical Pharmacology Testosterone clinical monograph accessed May 8 2025; https://www.clinicalkey.com/pharmacology/monograph/595?n=Testosterone
  2. https://go.drugbank.com/drugs/DB13944
  3. Mayo Clinic. Testosterone cypionate (intramuscular route). https://www.mayoclinic.org/drugs-supplements/testosterone-cypionate-intramuscular-route/description/drg-20563731
  4. Testosterone enanthate [package insert] Hikma Pharmaceuticals USA Inc. Berkeley Heights, NJ 07922, revised January 2021, accessed May 08 2025 through: https://www.accessdata.fda.gov/spl/data/d56a5e5d-c88f-4f0d-84b4-1be06ca6ebba/d56a5e5d-c88f-4f0d-84b4-1be06ca6ebba.xml
  5. Depo Testosterone(Testosterone Cypionate) [package insert] Pfizer Inc NY, NY 10017, revised July 2018, accessed May 08 2025 through: https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/085635s040lbl.pdf

WPPL operates as a 503A compounding pharmacy and prepares individualized prescription medications pursuant to provider direction. Compounded preparations are not reviewed, tested, or approved by the FDA.

This listing also includes commercially manufactured products for convenience; these items are not compounded by our pharmacy and are sold as provided by their manufacturers. Actual products in stock at time of dispensing may vary due to supply chain variability. Any statements regarding non-compounded products are manufacturer-supplied, have not been evaluated by the FDA, and are not intended to diagnose, treat, cure, or prevent any disease. WPPL does not verify or endorse any therapeutic claims made by manufacturers. Please refer to original labeling for complete product information.

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