atanoprost (LatanoSTIM) hair cream compounding

Latanoprost (LatanoSTIM) – Hair Cream

0.06%

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Disclaimer: Images are for reference only; actual products may vary.

Product Overview

Product Description

Latanoprost (LatanoSTIM) – Hair Cream Description^1-5

Latanoprost is a prostaglandin F2α (PGF2α) analog that is primarily indicated for the management of open-angle glaucoma and ocular hypertension. Evidence indicates that the drug is associated with hair growth, particularly in cases of androgenetic alopecia (AGA) and eyelash or eyebrow hypotrichosis. Its association with hair regrowth was initially observed as an adverse effect involving increased eyelash growth in patients treated for glaucoma.

Product Mechanism of Action

Mechanism of Action^1-5

Latanoprost binds to the prostaglandin F2α receptor on hair follicle dermal papilla cells, influencing the hair growth cycle as follows:

Prolongation of Anagen Phase (Growth Phase):

Increases the duration of anagen, resulting in longer and thicker hair shafts.

Stimulation of Melanogenesis:

May enhance pigmentation in vellus hairs, making them appear darker and more terminal-like.

Increased Follicular Density:

Some studies suggest latanoprost may increase the number of follicles actively producing hair, particularly in the eyelash and eyebrow regions, and potentially the scalp.

Product Adverse Reactions

Common^1-5

Local irritation (itching, burning, erythema)
Hyperpigmentation of skin (especially around eyelids or eyebrows)
Increased pigmentation of treated hair
Eyelid darkening (rare with scalp use)
Unwanted hair growth if medication spreads to unintended areas
Eye irritation (if it migrates to eye area)

Product Contraindications & Precautions

Contraindications / Precautions^1-5

Contraindications

Known hypersensitivity to latanoprost or prostaglandin analogs
Active ocular conditions if near eyes (without ophthalmologic approval)
History of herpetic keratitis (due to prostaglandin-induced reactivation risk)

Precautions

Avoid application near the eyes unless specifically prescribed
Use gloves or applicator to prevent unintended hair growth on fingers/hands
Avoid contact with mucous membranes
Patients with a history of uveitis, macular edema, or intraocular surgery should be monitored if periorbital application is required

Product Storage

Store refrigerated (2°C–8°C or 36°F–46°F); protect from light and heat.

Product References

Johnstone, M. A. (1997). Hypertrichosis and increased pigmentation of eyelashes and adjacent hair in latanoprost therapy. American Journal of Ophthalmology, 120(7), 999–1001.
Blume-Peytavi, U., et al. (2012). Latanoprost stimulates human scalp hair growth in vivo. Journal of the American Academy of Dermatology, 66(5), 807–814.
Kwon, O. S., et al. (2007). Prostaglandin analogs as a potential treatment for hair loss: Latanoprost and bimatoprost in the management of alopecia. International Journal of Dermatology, 46(9), 1044–1048.
Clinical Pharmacology. Elsevier. Latanoprost Monograph. Accessed 2025
FDA Drug Label: Xalatan (latanoprost ophthalmic solution) https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=a98595b3-9f47- 48e0-b18d-550a2095f264&type=display Revised May 2023. Accessed June 15, 2025

Product Disclaimer

WPPL operates as a 503A compounding pharmacy and prepares individualized prescription medications pursuant to provider direction. Compounded preparations are not reviewed, tested, or approved by the FDA.

This listing also includes commercially manufactured products for convenience; these items are not compounded by our pharmacy and are sold as provided by their manufacturers. Actual products in stock at time of dispensing may vary due to supply chain variability. Any statements regarding non-compounded products are manufacturer-supplied, have not been evaluated by the FDA, and are not intended to diagnose, treat, cure, or prevent any disease. WPPL does not verify or endorse any therapeutic claims made by manufacturers. Please refer to original labeling for complete product information.

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