Gonadorelin

Injection

1 mg Vial | 2 mg Vial

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Disclaimer: Images are for reference only; actual products may vary.

Product Overview Coming Soon

Product Overview

Product Description

Gonadorelin Description^1-5

Gonadorelin is a synthetic decapeptide that shares the identical amino acid sequence with naturally occurring gonadotropin-releasing hormone (GnRH). Both consist of 10 amino acids arranged in the sequence pyro-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH₂.

Clinically, gonadorelin is used as a diagnostic agent following pituitary surgery. In males, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) stimulate testosterone and sperm production. In females, FSH and LH are involved in regulation of the menstrual cycle and ovulation. Gonadorelin has a half-life ranging from approximately 2 to 40 minutes.

References

DrugBank. Gonadorelin: Uses, Interactions, Mechanism of Action.
https://go.drugbank.com/drugs/DB00644
RxList. Factrel (Gonadorelin): Side Effects, Uses, Dosage https://www.rxlist.com/factrel-drug.htm#description. August 8, 2022
Medicines.org.uk. Gonadorelin 100 mcg Powder for Solution for Injection – SmPC.
https://www.medicines.org.uk/emc/product/4853/smpc
DailyMed. GONABREED – Gonadorelin Injection, Solution.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9bc44a48-ff45-468a-a60d-c490a667
Gonadorelin’s Potential Interactions With The Hypothalamic-Pituitary-Gonadal Axis https://www.corepeptides.com/gonadorelins-potential-interactions-with-the-hypothalamic-pituitary-gonadal-axis/ June 7, 2025 Accessed July 14, 2025

Product Mechanism of Action

Mechanism of Action^1-5

GnRH is made in the hypothalamus and functions to stimulate the release of follicle stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. This increase in FSH and LH may stimulate the production and release of testosterone by the male testes and estrogen by the female ovaries and placenta.

Product Adverse Reactions

Common^1-5

Headache
Nausea
Abdominal discomfort
Flushing
Dizziness or lightheadedness
Injection site reactions such as redness, pain, or swelling

Product Contraindications & Precautions

Contraindications^1,2,4

Intolerance or hypersensitivity to gonadorelin
Use in pregnant or breastfeeding women is contraindicated

Precautions^1,2,4

Rare instances of hypersensitivity reaction (bronchospasm, tachycardia, flushing, urticaria, induration at injection site) and anaphylactic reactions have been reported following multiple-dose administration.
There has been a report of pituitary apoplexy and sudden blindness following gonadotropin-releasing hormone administration to a patient with a gonadotropin-secreting adenoma.

Product Storage

Store refrigerated at 36°F to 46°F (2°C – 8°C). Discard 28 days after mixing. Do not freeze. Keep out of reach of children and pets.

Product References

DrugBank. Gonadorelin: Uses, Interactions, Mechanism of Action.
https://go.drugbank.com/drugs/DB00644
RxList. Factrel (Gonadorelin): Side Effects, Uses, Dosage https://www.rxlist.com/factrel-drug.htm#description. August 8, 2022
Medicines.org.uk. Gonadorelin 100 mcg Powder for Solution for Injection – SmPC.
https://www.medicines.org.uk/emc/product/4853/smpc
DailyMed. GONABREED – Gonadorelin Injection, Solution.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9bc44a48-ff45-468a-a60d-c490a667
Gonadorelin’s Potential Interactions With The Hypothalamic-Pituitary-Gonadal Axis https://www.corepeptides.com/gonadorelins-potential-interactions-with-the-hypothalamic-pituitary-gonadal-axis/ June 7, 2025 Accessed July 14, 2025

Product Disclaimer

This information is for educational purposes only.

This compounded product has not been reviewed, approved, or evaluated by the Food and Drug Administration for safety and effectiveness. This product is not intended to diagnose, treat, cure, or prevent any disease. No claims are made regarding treatment, cure, or prevention of any disease or condition.

This information is a summary. It may not cover all possible drug information about this product. For complete product information, refer to the manufacturer’s prescribing information and labeling. Call your doctor for medical advice and/or about side effects. You may report side effects to the FDA at 1-800-FDA-1088. A WP Pharma Labs pharmacist will be happy to answer any questions. For consultation, please call 1-800-441-0048.

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