DHEA-7-Keto SR K100M

Capsule

100 mg

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Disclaimer: Images are for reference only; actual products may vary.

Product Overview

DHEA-7-Keto SR K100M Description1-4

7-Keto-DHEA is a naturally occurring metabolite of dehydroepiandrosterone (DHEA). Unlike DHEA, it does not convert into sex hormones such as testosterone or estradiol. Evidence suggests potential effectiveness in areas including weight management, metabolic support, immune function, and cognitive performance.

Mechanism of Action1,2

7-Keto-DHEA is believed to enhance thermogenesis (heat production) and basal metabolic rate by modulating the activity of 3 key metabolic enzymes, including: Glycerol-3-phosphate dehydrogenase, cytosolic malic enzyme, citrate lyase.

These enzymes influence fatty acid oxidation and mitochondrial efficiency, contributing to increased energy expenditure by cells.

Adverse Reactions1,2

  • Headache
  • Nausea or gastrointestinal upset
  • Mild dizziness
  • Irritability
  • Sleep disturbances (less common)
  • Because it does not convert into sex hormones, androgenic side effects (e.g., acne, hair loss, hirsutism) are rare or absent

Contraindications1,2

  • Hypersensitivity to 7-keto-DHEA or any excipients in the product.
  • Pregnancy or breastfeeding (insufficient safety data).

 

Precautions1,2

  • Use caution in individuals with autoimmune diseases due to theoretical immune-enhancing effects.
  • May interfere with thyroid function tests (e.g., T3/T4 levels); however, clinical significance is unclear.
  • People with hormone-sensitive conditions may still want to consult a healthcare provider, even though 7-keto-DHEA lacks direct hormonal activity.
  • Safety in children and adolescents has not been established.
  • Store at controlled room temperature (20°C to 25°C / 68°F to 77°F)
  • Protect from moisture and light
  • Keep in a tightly closed container
  1. 7-Keto DHEA – Patient Handout; NatMed Pro; 2025; https://naturalmedicines-therapeuticresearch-com.lp.hscl.ufl.edu/databases/food,-herbs-supplements/patienthandout.aspx?productid=835&lang=en
  2. 7-Keto DHEA – Professional Monograph; NatMed Pro; 2025; https://naturalmedicines-therapeuticresearch-com.lp.hscl.ufl.edu/databases/food,-herbs-supplements/professional.aspx?productid=835
  3. Douglas S. Kaiman, Carlon M. Colker, Melissa A. Swain, Georgeann C. Torina, Qiuhu Shi. A randomized, double-blind, placebo-controlled study of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy overweight adults. Current Therapeutic Research. Volume 61, Issue 7, 2000, 435-442.
  4. Jeyaprakash N, Maeder S, Janka H, Stute P. A systematic review of the impact of 7-keto-DHEA on body weight. Arch Gynecol Obstet. 2023 Sep;308(3):777-785.

WPPL operates as a 503A compounding pharmacy and prepares individualized prescription medications pursuant to provider direction. Compounded preparations are not reviewed, tested, or approved by the FDA.

This listing also includes commercially manufactured products for convenience; these items are not compounded by our pharmacy and are sold as provided by their manufacturers. Actual products in stock at time of dispensing may vary due to supply chain variability. Any statements regarding non-compounded products are manufacturer-supplied, have not been evaluated by the FDA, and are not intended to diagnose, treat, cure, or prevent any disease. WPPL does not verify or endorse any therapeutic claims made by manufacturers. Please refer to original labeling for complete product information.

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