Topical Peel
30%
Product Overview
Glycolic Acid (W/V) Description1,2
In dermatology, peels are a technique used to exfoliate the epidermal layer of the skin. Glycolic acid (GA), an alpha-hydroxy acid derived from sugarcane, is the most commonly used alpha-hydroxy acid for peels. GA peels can be prepared at varying pH levels and concentrations depending on the desired depth of exfoliation. They are formulated as free acids (low pH), partially neutralized solutions (higher pH), buffered solutions, or esterified solutions, with concentrations ranging from 20% to 70%. GA peels are used in the management of acne vulgaris, melasma, wrinkles, actinic keratosis, photodamage, photoaging, pigmentation disorders, and acne scars.
Mechanism of Action1,2
Therapeutically, GA peels can have anti-inflammatory, keratolytic, and antioxidant effects depending on the indication for the treatment. Mechanistically, GA targets the corneosome by enhancing breakdown and decreasing cohesiveness, causing desquamation. Peel intensity is determined by four factors 1) the concentration of the acid, 2) the vehicle used to carry it, 3) the amount of acid applied, and 4) the technique used. To neutralize the acidification, water or basic solutions such as ammonium salts, sodium bicarbonate, or sodium hydroxide are used. In addition, to the keratolytic activity of GA, it can increase the production of collagen in the dermis (the deeper layer of the skin). This can add integrity to the skin. Lastly, GA can facilitate the development of lipids in the epidermis, such as ceramides and cholesterol, which has a vital role in upholding a healthy skin barrier. By fortifying the barrier function, GA helps to prevent transepidermal water loss. This maintains optimal hydration of the skin.
Common1,3
Contraindications3
Precautions3
Store at 20–25°C (68–77°F) in a cool, dry place. Protect from light and moisture to maintain stability.
WPPL operates as a 503A compounding pharmacy and prepares individualized prescription medications pursuant to provider direction. Compounded preparations are not reviewed, tested, or approved by the FDA.
This listing also includes commercially manufactured products for convenience; these items are not compounded by our pharmacy and are sold as provided by their manufacturers. Actual products in stock at time of dispensing may vary due to supply chain variability. Any statements regarding non-compounded products are manufacturer-supplied, have not been evaluated by the FDA, and are not intended to diagnose, treat, cure, or prevent any disease. WPPL does not verify or endorse any therapeutic claims made by manufacturers. Please refer to original labeling for complete product information.
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Providers: Let’s Partner for Better Patient Care
If you are a physician, clinic, or practice seeking a dependable Compounding Pharmacy partner, WP Pharma Labs is here to help. With dedicated account setup, streamlined ordering and responsive service, we support your therapeutic goals with specialized compounds designed for your patients.
To check product availability, check on the status of an existing order, request refills:
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